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Clinical Evidence Although the evidence base is less extensive than for topical or laser interventions, a number of studies and reviews support mesotherapy as an adjunct or alternative in melasma management

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however, those with kidney disease should consult their renal team before use Caffeine (from coffee or tea) may enhance endurance and reduce perceived exertion, though it may worsen palpitations, anxiety, or blood pressure in some individuals General lifestyle approaches that support the same health goals as beetroot extract include: Regular physical activity (150 minutes of moderate-intensity exercise weekly, as per NHS guidelines) Maintaining a healthy body weight Limiting alcohol consumption Smoking cessation Stress management techniques Before starting any alternative supplement or making significant dietary changes, particularly if you have existing health conditions, consult your GP or a registered dietitian